{"id":122508,"date":"2021-10-06T23:30:59","date_gmt":"2021-10-06T23:30:59","guid":{"rendered":"https:\/\/fin2me.com\/?p=122508"},"modified":"2021-10-06T23:30:59","modified_gmt":"2021-10-06T23:30:59","slug":"who-backs-malaria-vaccine-rollout-for-africas-children-in-major-breakthrough","status":"publish","type":"post","link":"https:\/\/fin2me.com\/markets\/who-backs-malaria-vaccine-rollout-for-africas-children-in-major-breakthrough\/","title":{"rendered":"WHO backs malaria vaccine rollout for Africa's children in major breakthrough"},"content":{"rendered":"

NAIROBI (Reuters) – The World Health Organization (WHO) said on Wednesday the only approved vaccine against malaria should be widely given to African children, potentially marking a major advance against a disease that kills hundreds of thousands of people annually.<\/p>

FILE PHOTO: A logo is pictured at the World Health Organization (WHO) building in Geneva, Switzerland, February 2, 2020. REUTERS\/Denis Balibouse<\/figcaption>

The WHO recommendation is for RTS,S – or Mosquirix – a vaccine developed by British drugmaker GlaxoSmithKline.<\/p>\n

Since 2019, 2.3 million doses of Mosquirix have been administered to infants in Ghana, Kenya and Malawi in a large-scale pilot programme coordinated by the WHO. The majority of those whom the disease kills are under age five.<\/p>\n

That programme followed a decade of clinical trials in seven African countries.<\/p>\n

\u201cThis is a vaccine developed in Africa by African scientists and we\u2019re very proud,\u201d said WHO director-general Tedros Adhanom Ghebreyesus.<\/p>\n

\u201cUsing this vaccine in addition to existing tools to prevent malaria could save tens of thousands of young lives each year,\u201d he added, referring to anti-malaria measures like bed nets and spraying to kill mosquitoes that transmit the disease.<\/p>\n

One of the ingredients in the Mosquirix vaccine is sourced from a rare evergreen native to Chile called a Quillay tree. Reuters reported on Wednesday here that the long-term supply of these trees is in question.<\/p>\n

Malaria is far more deadly than COVID-19 in Africa. It killed 386,000 Africans in 2019, according to a WHO estimate, compared with 212,000 confirmed COVID-19 deaths in the past 18 months.<\/p>\n

The WHO says 94% of malaria cases and deaths occur in Africa, a continent of 1.3 billion people. The preventable disease is caused by parasites transmitted to people by the bites of infected mosquitoes. Symptoms include fever, vomiting and fatigue.<\/p>\n

The vaccine\u2019s effectiveness at preventing severe cases of malaria in children is only around 30%, but it is the only approved vaccine. The European Union\u2019s drugs regulator approved it in 2015, saying its benefits outweighed the risks.<\/p>\n

\u201cThis is how we fight malaria, layering imperfect tools on top of each other,\u201d said Ashley Birkett, who leads global malaria vaccine work at Path, a non-profit global health organization that has funded development of the vaccine with GSK and the three-country pilot.<\/p>\n

Another vaccine against malaria called R21\/Matrix-M that was developed by scientists at Britain\u2019s University of Oxford showed up to 77% efficacy in a year-long study involving 450 children in Burkina Faso, researchers said in April. It is still in the trial stages.<\/p>\n

GSK welcomed the WHO recommendation.<\/p>\n

\u201cThis long-awaited landmark decision can reinvigorate the fight against malaria in the region at a time when progress on malaria control has stalled,\u201d Thomas Breuer, GSK\u2019s chief global health officer, said in a statement.<\/p>\n

GSK shares held steady in New York following the announcement, which came after the close of trading in its London-listed shares.<\/p>\n

FUNDING CHALLENGE<\/h2>\n

The recommendation was jointly announced in Geneva by the WHO\u2019s top advisory bodies for malaria and immunization, the Malaria Policy Advisory Group and the Strategic Advisory Group of Experts on Immunization.<\/p>\n

Experts said the challenge now would be mobilising financing for production and distribution of the vaccine to some of the world\u2019s poorest countries.<\/p>\n

GSK has to date committed to produce 15 million doses of Mosquirix annually up to 2028 at a cost of production plus no more than 5% margin.<\/p>\n

A global market study led by the WHO this year projected demand for a malaria vaccine would be 50 to 110 million doses per year by 2030 if it is deployed in areas with moderate to high transmission of the disease.<\/p>\n

The GAVI vaccine alliance, a global public-private partnership, will consider in December whether and how to finance the vaccination programme.<\/p>\n

\u201cAs we\u2019ve seen from the COVID vaccine, where there is political will, there is funding available to ensure that vaccines are scaled to the level they are needed,\u201d said Kate O\u2019Brien, director of WHO\u2019s Department of Immunization, Vaccines and Biologicals.<\/p>\n

A source familiar with planning for the vaccine\u2019s development said the price per dose was not yet set, but would be confirmed after GAVI\u2019s funding decision and once there is a clear sense of demand.<\/p>\n

The WHO\u2019s decision had personal meaning for Dr. Rose Jalong\u2019o, a vaccinology specialist at the Kenyan health ministry.<\/p>\n

\u201cI suffered from malaria as a child, and during my internship, and during my clinical years I attended to children in hospital because of severe malaria who needed blood transfusion and unfortunately some of them died,\u201d she said.<\/p>\n

\u201cIt\u2019s a disease I have grown up with and, seeing all this in my lifetime, it\u2019s an exciting time.\u201d<\/p>\n

Source: Read Full Article<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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